Getting ready to talk to your infertility specialis
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Getting ready to talk to your infertility specialist

Not knowing can be stressful. That's why we've laid out everything you need to know to be prepared for your visit to the clinic.

Preparing for the clinic

Your first visit to a fertility clinic will typically be with your reproductive endocrinologist (REI) and fertility nurses. A combination of conversation and examination, this visit will give your team important information about you and your partner. These insights about your medical histories, lifestyles, and physical attributes are crucial for determining the cause of—and best treatment for—your conception challenges.

What women can expect at the clinic

    

      

Conversation

You will talk to your doctor about your medical history, including details on your period, past pregnancies and surgeries, sexually transmitted diseases, and medication use including birth control. Your diet, exercise habits, work environment, and current sexual practices will also be discussed.

Examination

A woman must have working ovaries, fallopian tubes, and a uterus in order to become pregnant. Your doctor needs to examine your body and perform a series of tests to identify reproductive system conditions or abnormalities that may be contributing to your fertility challenges. Procedures may vary by clinic, but usually include:

 

  • Physical, pelvic and genital, breast, and thyroid exams
  • General health tests for diseases, disorders, or medical conditions
  • Blood and urine tests
  • Ultrasounds of your uterus and ovaries throughout your menstrual cycle
Advanced testing

Depending on the results from your initial discussion and examination, your doctor may order additional fertility tests and procedures to better understand how your reproductive system is functioning.

  • Hormone blood and urine tests help determine if you are ovulating, and the quality and quantity of the eggs you're producing (also known as your ovarian reserve). This can help predict how your ovaries will respond to infertility treatment cycles in the future.
    Blood tests include:
    • Follicle stimulating hormone (FSH) and estradiol (estrogen) taken on day 3 of your period
    • Progesterone taken approximately 1 week prior to your expected period
    • Additional hormones including luteinizing hormone (LH), prolactin, testosterone, anti-Müllerian hormone (AMH), and thyroid stimulating hormone (TSH)
  • Ultrasound scan to review the size and number of follicles present in the ovaries (called antral follicle count)
  • Hysterosalpingogram (HSG), a test that uses colored dye and an X-ray to identify tubal blockages or cysts
  • Hysteroscopy, used to diagnose or treat problems in the uterus. A tiny, lighted scope will be inserted through your cervix to project images of your uterus onto a screen. The removal of a small piece of tissue from the uterine lining (called endometrial biopsy) may be performed at the same time
  • Laparoscopy to check for blockages, growths, or signs of endometriosis around the uterus and fallopian tubes. Your doctor will use a small, surgical scope that’s inserted into the abdomen under general anesthesia
  • Sonohysterogram, a special ultrasound exam that uses saline to inflate your uterine cavity to provide a more detailed picture of the uterus than traditional ultrasound

What men can expect at the clinic

    

     

Conversation

Your doctor will ask a series of questions about your medical history, including groin injuries, prior surgeries, medication use, and history of genital medical conditions like undescended testicles, urinary problems, impotence or ejaculatory problems, and sexually transmitted diseases.


You will also be asked about your diet, exercise routine, work environment, and current sexual practices, and whether you smoke, drink, or use drugs.

Examination

To father a child, a male must develop sperm of healthy quality and quantity, a functioning reproductive tract, and unblocked sperm ducts. A men’s health specialist will use examinations and tests to help diagnose and treat male factor infertility if it exists. 

 

You can expect some or all of the following tests:

 

  • Physical exam of your penis, testicles, prostate gland, and scrotum
  • General health tests for diseases, disorders, or medical conditions
  • Hormone blood and urine tests
  • Semen analysis to check sperm count, quality, and movement
  • Testicular biopsy if no sperm are present in your semen sample
Advanced testing

After reviewing results from this initial visit, your doctor may want to conduct advanced tests and procedures such as:

 

  • Transscrotal ultrasound to identify blockages or varicose veins around your testicles or sperm ducts. A small device will be passed back and forth over your scrotum to pick up soundwaves that are converted into an image
  • Transrectal ultrasound for thorough overview of your prostate, the glands that produce semen (called seminal vesicles), and the duct that carries sperm from your testicles to your urethra (called the vas deferens). This is done using a thin probe inserted into your rectum while you lie on your side, a procedure most men find uncomfortable, but painless
  • Repeat semen analysis if your initial semen analysis results are abnormal. Lab personnel will check for live sperm and confirm there are no antibodies or infections in your semen
  • Advanced sperm testing, an additional analysis ordered if your preliminary examination indicates there may be a problem. This will provide more details on the overall health status of your sperm

What to ask at your first appointments

With so much new information coming your way, first visits can be a bit of a whirlwind. But the more prepared you are, the more comfortable you’ll feel. Bring these discussion guides along to your consults to help guide conversation and remind you of important questions to ask your doctor.

Discussion guides

Fertility Testing and Treatment
Egg and Embryo Freezing
LGBTQ Family Building

       

Finding support

Learn where to turn for guidance while struggling with infertility

Get support
Finding support

Medication savings

See programs that may reduce the cost of treatment

See programs
Medication savings

QUESTIONS?

Call 1-866-LETS-TRY to talk to a Fertility LifeLines® representative today.

or send an email

IMPORTANT RISK INFORMATION & INDICATIONS AND USAGE

Summary of Contraindications

Gonal-f® RFF* Redi-ject®, Gonal-f® Multi-Dose and Gonal-f® RFF* 75 IU are contraindicated in patients with prior hypersensitivity to rhFSH or excipients, high levels of FSH indicating primary gonadal failure, pregnancy, uncontrolled thyroid, adrenal or pituitary disorders, sex hormone dependent tumors of the reproductive tract/accessory organs, tumors of pituitary gland or hypothalamus, abnormal uterine bleeding of undetermined origin and ovarian cyst or enlargement of undetermined origin.

Please scroll for full IMPORTANT RISK INFORMATION or see full Prescribing Information for Gonal-f® RFF* Redi-ject®, Gonal-f® Multi-Dose and Gonal-f® RFF* 75 IU.

* RFF: Revised Formulation Female

Important Risk Information for Gonal-f® RFF* Redi-ject® (follitropin alfa injection)

Do not use Gonal‐f® RFF* Redi‐ject® if you:

  • are allergic to recombinant human FSH or any of the ingredients listed on the product carton or package insert
  • have levels of FSH indicating primary gonadal failure
  • are pregnant or think you may be pregnant due to the potential hazard to a fetus
  • have uncontrolled thyroid, adrenal or pituitary problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal bleeding from your uterus or vagina
  • have ovarian cysts or large ovaries with unknown cause, not due to polycystic ovary syndrome (PCOS)

Before using Gonal‐f® RFF* Redi‐ject®, tell your healthcare provider about your medical history including any prescription or over- the-counter medicines, vitamins and herbal supplements used, whether you have or have had asthma, abdominal surgery, ovarian cysts, polycystic ovarian disease, blood clots (thrombosis) or family history of blood clots, or are breastfeeding or plan to breastfeed.

Gonal‐f® RFF* Redi‐ject® may cause serious side effects, including:

  • Severe or fatal allergic reactions. Stop using Gonal‐f® RFF* Redi‐ject® and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).
  • Stomach bloating or pain caused by enlargement of your ovaries, or fluid build-up in your stomach, chest and heart caused by ovarian hyperstimulation syndrome (OHSS). OHSS can require hospitalization and in rare cases has caused death. Call your healthcare provider right away if you have symptoms of OHSS, including trouble breathing, severe lower stomach (pelvic) area pain, decreased urine output, nausea, vomiting, weight gain, and diarrhea. 
  • Gonal-f® RFF* can also cause or worsen lung problems (including severe shortness of breath and asthma), blood and blood vessel problems (including clots and stroke) which in rare cases have caused death. 
  • Twisting of your ovary, which requires medical attention.
  • Chances of having a baby with birth defects may increase in a baby born after an ART cycle and can be impacted by maternal age, paternal sperm problems, and genetic background associated with the egg and sperm.
  • Use of Gonal‐f® RFF* Redi‐ject® can result in pregnancy with more than 1 baby and the birth of multiple babies. 
  • Ectopic pregnancy (pregnancy outside your womb).
  • An increased risk of miscarriage. 
  • If you have used fertility medicines like Gonal‐f® RFF* Redi‐ject® before to get pregnant, you may have an increased chance of having tumors in your ovary(ies) (including cancer).
  • Ultrasound and lab tests should be used to monitor treatment.

The most common side effects of Gonal‐f® RFF* Redi‐ject® include:

  • In Ovulation Induction headache, abdominal pain, and ovarian hyperstimulation
  • In ART - abdominal pain, nausea, abdominal enlargement, headache and injection site bruising 

These are not all the possible side effects of Gonal‐f® RFF* Redi‐ject®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® RFF* Redi‐ject® as directed and do not change your dose unless directed. Do not share your Gonal‐f® RFF* Redi‐ject® and needles with another person; you may give another person an infection or get an infection from them.

Carefully review the Gonal‐f® RFF* Redi‐ject® Instructions for Use that comes with the Pen for information about the correct use of Gonal‐f® RFF* Redi‐ject® and follow all training and instruction provided by your healthcare provider.

Indications and Usage

Gonal‐f® RFF* Redi‐ject® (follitropin alfa injection) is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program 

 For complete information, please see full Prescribing information here.

*RFF, Revised Formulation Female

Important Risk Information for Gonal-f® Multi-Dose (follitropin alfa for injection)

Do not use Gonal‐f® Multi-Dose if you:

  • Are allergic to recombinant human FSH or any of the ingredients listed on the product carton or insert
  • Have uncontrolled thyroid or adrenal problems
  • Have a tumor in your female organs, including your ovaries, breast, or uterus or permanent damage to the male sex organs (testes)
  • Have a tumor in your brain, such as a tumor in your pituitary 
  • Have abnormal bleeding from your uterus or vagina
  • Have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)
  • Are pregnant or think you may be pregnant

Before using Gonal‐f® Multi-Dose, tell your healthcare provider about your medical history including any prescription or over- the-counter medicines, vitamins and herbal supplements used, whether you have or have had asthma, abdominal surgery, ovarian cysts, polycystic ovarian disease, blood clots (thrombosis) or family history of blood clots, or are breastfeeding or plan to breastfeed.

Gonal‐f® Multi-Dose may cause serious side effects, including:

  • Ovarian hyperstimulation syndrome (OHSS) is a serious side effect. OHSS can be mild, moderate or severe, and in rare cases, has caused death. Mild symptoms can progress to more serious symptoms and immediate evaluation by your doctor is necessary. Early signs of OHSS include trouble breathing, severe lower stomach (pelvic) area pain, nausea, vomiting, weight gain. Call your health care provider right away. Symptoms include stomach pain, stomach bloating, nausea, vomiting and diarrhea, enlargement of ovaries, difficulty breathing and a drop in urine output
  • Gonal-f® Multi-Dose can also cause or worsen lung problems (including acute respiratory distress syndrome and asthma), blood and blood vessel problems (including clots and stroke) which in rare cases have caused death.
  • Use of Gonal‐f® Multi-Dose can result in pregnancy with more than one baby and the birth of multiple babies.
  • Stop using Gonal‐f® and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).

Other serious side effects include:

  • Gonal‐f® Multi-Dose can also cause or worsen lung problems (including asthma), blood and blood vessel problems (including clots and stroke), or twisting of your ovary, which require medical attention
  • Miscarriage, or ectopic pregnancy (pregnancy outside your womb)
  • Chances of having a baby with birth defects may increase in a baby born after an ART cycle and can be impacted by maternal age, paternal sperm problems, and genetic background associated with the egg and sperm.
  • It is not known if this drug is excreted in human milk. Because of the potential for serious adverse reactions in the nursing infant from Gonal-f, a decision should be made whether to stop nursing or stop the drug taking into account the importance of the drug to the mother.

The most common side effects of Gonal‐f® Multi-Dose include 

  • Headache 
  • Stomach pain 
  • Stomach bloating 
  • Bruising at the injection site,
  • Nausea
  • Other side effects reported include sinus infections and ovarian cysts.

In men, common side effects include 

  • Skin pimples 
  • Breast pain and growth
  • Tiredness.

These are not all the possible side effects of Gonal‐f®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® Multi-Dose as directed and do not change your dose unless directed. Do not share your Gonal‐f® Multi-Dose and needles with another person; you may give another person an infection or get an infection from them.

Carefully review the Gonal‐f® Multi‐Dose Patient Information Leaflet that comes with the product and follow all training and instruction provided by your healthcare provider. The injection syringes provided with the product should only be used with Gonal‐f® Multi‐Dose and should not be used to administer any other drug or hormone.

Indications and Usage

Gonal‐f® Multi-Dose is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • Help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • Cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program

Gonal‐f® Multi-Dose can also be prescribed to increase sperm production in men with a rare medical condition.

 

Important Risk Information for Gonal-f® RFF* 75 IU (follitropin alfa for injection)

Do not use Gonal‐f® RFF* 75 IU if you:

  • are allergic to recombinant human FSH or any of the ingredients listed on the product carton or package insert
  • have levels of FSH indicating primary gonadal failure
  • have uncontrolled thyroid or adrenal problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal uterine bleeding of undetermined origin
  • have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)
  • are pregnant or think you may be pregnant

Before using Gonal-f® RFF* 75 IU, tell your healthcare provider about your medical history including any prescription or over-the-counter medicines, vitamins and herbal supplements used.

Gonal‐f® RFF* 75 IU may cause serious side effects, including: 

  • Severe or fatal allergic reactions. Stop using Gonal‐f® RFF* 75 IU and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).
  • Stomach bloating or pain caused by enlargement of your ovaries, or fluid build-up in your stomach, chest and heart caused by ovarian hyperstimulation syndrome (OHSS). OHSS can require hospitalization and in rare cases has caused death. Call your healthcare provider right away if you have symptoms of OHSS, including trouble breathing, severe lower stomach (pelvic) area pain, decreased urine output, nausea, vomiting, weight gain, and diarrhea. 
  • Gonal‐f® RFF* 75 IU can also cause or worsen lung problems (including asthma), blood and blood vessel problems (including clots and stroke), or twisting of your ovary, which require medical attention.
  • Use of Gonal‐f® RFF* 75 IU can result in pregnancy with more than one baby and the birth of multiple babies. 
  • It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in the nursing infant from Gonal-f® RFF* 75 IU, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

The most common side effects of Gonal‐f® RFF* 75 IU include headache, stomach pain, stomach bloating, bruising at the injection site, and nausea. Other side effects reported include sinus infections and ovarian cysts. 

These are not all the possible side effects of Gonal‐f® RFF* 75 IU. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® RFF* 75 IU as directed and do not change your dose unless directed. Do not share your Gonal‐f® RFF* 75 IU and needles with another person; you may give another person an infection or get an infection from them.

Indications and Usage

Gonal‐f® RFF* 75 IU (follitropin alfa for injection) is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • cause your ovaries to develop multiple (more than one) eggs as part of an Assisted Reproductive Technology (ART) program
*RFF, Revised Formulation Female

Important Risk Information for Cetrotide® (cetrorelix acetate for injection)

Who should not use Cetrotide®?

  • Patients that are allergic to cetrorelix acetate, mannitol, or exogenous peptide hormones (medicines similar to Cetrotide®) should not use Cetrotide®
  • If you have had severe allergic reactions to any drugs in a previous IVF cycle, tell your doctor.
  • Cetrotide® should not be used in patients who are pregnant, think they might be pregnant, or are breastfeeding.
  • Cetrotide® should not be used in patients with kidney disease.

Before starting Cetrotide®, tell your healthcare professional about all your medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

What is the most important information I should know before starting Cetrotide®?

  • Your doctor will confirm you are not pregnant.

What are the possible side effects of Cetrotide®?

Cetrotide® may cause serious side effects including:

  • Allergic reactions including anaphylactic reaction with the first dose. Treatment with Cetrotide® is not advised in women with severe allergic conditions.
  • Your doctor should review with you the risks and benefits of using Cetrotide®.
  • It is not known if Cetrotide® is excreted in human milk. Because the effects of Cetrotide® on nursing mothers or the nursing infant are not known, do not use Cetrotide® if you are breastfeeding.

Common side effects of using Cetrotide® include:

  • Mild and short-lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

These are not all the possible side effects of Cetrotide®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Indication

What are the uses of Cetrotide®?

Cetrotide® blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

Cetrotide® blocks undesirable premature ovulation. Premature ovulation may lead to eggs that are not available for egg retrieval.

 Please see full Prescribing information here.

Important Risk Information for Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)

Who should not use Ovidrel® PreFilled Syringe?

Ovidrel® Pre-Filled Syringe should not be used in patients:

  • With allergies to hCG or any other ingredients in the medication
  • With primary ovarian failure (the ovaries no longer produce eggs)
  • With uncontrolled thyroid or adrenal disease
  • Cancer of the brain such as pituitary tumor
  • With a history of abnormal bleeding from the uterus or vagina
  • With swollen, enlarged, or painful ovaries
  • With cancer of the sex organs
  • Who are pregnant 

Before starting Ovidrel®, tell your healthcare professional about all your medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What is the most important information I should know before taking Ovidrel?

  • Mild to moderate uncomplicated ovarian enlargement which may be accompanied by abdominal distention and/or abdominal pain may occur in patients treated with FSH and hCG. 
  • Ovarian Hyperstimulation Syndrome (OHSS) may progress rapidly from uncomplicated ovarian enlargement and become a serious medical event. Early signs of OHSS include severe pelvic pain, nausea, vomiting, and weight gain. Call your doctor right away if you think you might be having symptoms of OHSS.
  • Treatment with Ovidrel® may result in becoming pregnant with more than one baby.
  • Blood clots may result from treatment with Ovidrel®.
  • It is not known whether this drug is present in human milk. Because many drugs are excreted in human milk, tell your doctor if you are nursing.

What are the most common side effects of Ovidrel® Pre-Filled Syringe?

The most common side effects in women using Ovidrel® Pre-Filled Syringe include abdominal pain, nausea, and vomiting. Needle injections may cause some discomfort.

These are not all the possible side effects of Ovidrel®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Indication

What are the uses of Ovidrel® Pre-Filled Syringe (choriogonadotropin alfa for injection)?

Ovidrel® Pre-Filled Syringe (choriogonadotropin alfa injection) is indicated for the final egg maturation to get ready for egg retrieval. Women who receive Ovidrel® have undergone pituitary desensitization and have been appropriately pre-treated with follicle stimulating hormone (FSH) as a part of an Assisted Reproductive Technology (ART) program such as in vitro (IVF) fertilization and embryo transfer.

Ovidrel® Pre-Filled Syringe is also indicated for the induction of ovulation (OI) and pregnancy in infertile patients who do not ovulate, and in whom the cause of infertility is functional and not due to primary ovarian failure

 For complete information, please see full Prescribing information here.

IMPORTANT RISK INFORMATION & INDICATIONS AND USAGE

Summary of Contraindications

Gonal-f® RFF* Redi-ject®, Gonal-f® Multi-Dose and Gonal-f® RFF* 75 IU are contraindicated in patients with prior hypersensitivity to rhFSH or excipients, high levels of FSH indicating primary gonadal failure, pregnancy, uncontrolled thyroid, adrenal or pituitary disorders, sex hormone dependent tumors of the reproductive tract/accessory organs, tumors of pituitary gland or hypothalamus, abnormal uterine bleeding of undetermined origin and ovarian cyst or enlargement of undetermined origin.

Please scroll for full IMPORTANT RISK INFORMATION or see full Prescribing Information for Gonal-f® RFF* Redi-ject®, Gonal-f® Multi-Dose and Gonal-f® RFF* 75 IU.

* RFF: Revised Formulation Female

Important Risk Information for Gonal-f® RFF* Redi-ject® (follitropin alfa injection)

Do not use Gonal‐f® RFF* Redi‐ject® if you:

  • are allergic to recombinant human FSH or any of the ingredients listed on the product carton or package insert
  • have levels of FSH indicating primary gonadal failure
  • are pregnant or think you may be pregnant due to the potential hazard to a fetus
  • have uncontrolled thyroid, adrenal or pituitary problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal bleeding from your uterus or vagina
  • have ovarian cysts or large ovaries with unknown cause, not due to polycystic ovary syndrome (PCOS)

Before using Gonal‐f® RFF* Redi‐ject®, tell your healthcare provider about your medical history including any prescription or over- the-counter medicines, vitamins and herbal supplements used, whether you have or have had asthma, abdominal surgery, ovarian cysts, polycystic ovarian disease, blood clots (thrombosis) or family history of blood clots, or are breastfeeding or plan to breastfeed.

Gonal‐f® RFF* Redi‐ject® may cause serious side effects, including:

  • Severe or fatal allergic reactions. Stop using Gonal‐f® RFF* Redi‐ject® and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).
  • Stomach bloating or pain caused by enlargement of your ovaries, or fluid build-up in your stomach, chest and heart caused by ovarian hyperstimulation syndrome (OHSS). OHSS can require hospitalization and in rare cases has caused death. Call your healthcare provider right away if you have symptoms of OHSS, including trouble breathing, severe lower stomach (pelvic) area pain, decreased urine output, nausea, vomiting, weight gain, and diarrhea. 
  • Gonal-f® RFF* can also cause or worsen lung problems (including severe shortness of breath and asthma), blood and blood vessel problems (including clots and stroke) which in rare cases have caused death. 
  • Twisting of your ovary, which requires medical attention.
  • Chances of having a baby with birth defects may increase in a baby born after an ART cycle and can be impacted by maternal age, paternal sperm problems, and genetic background associated with the egg and sperm.
  • Use of Gonal‐f® RFF* Redi‐ject® can result in pregnancy with more than 1 baby and the birth of multiple babies. 
  • Ectopic pregnancy (pregnancy outside your womb).
  • An increased risk of miscarriage. 
  • If you have used fertility medicines like Gonal‐f® RFF* Redi‐ject® before to get pregnant, you may have an increased chance of having tumors in your ovary(ies) (including cancer).
  • Ultrasound and lab tests should be used to monitor treatment.

The most common side effects of Gonal‐f® RFF* Redi‐ject® include:

  • In Ovulation Induction headache, abdominal pain, and ovarian hyperstimulation
  • In ART - abdominal pain, nausea, abdominal enlargement, headache and injection site bruising 

These are not all the possible side effects of Gonal‐f® RFF* Redi‐ject®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® RFF* Redi‐ject® as directed and do not change your dose unless directed. Do not share your Gonal‐f® RFF* Redi‐ject® and needles with another person; you may give another person an infection or get an infection from them.

Carefully review the Gonal‐f® RFF* Redi‐ject® Instructions for Use that comes with the Pen for information about the correct use of Gonal‐f® RFF* Redi‐ject® and follow all training and instruction provided by your healthcare provider.

Indications and Usage

Gonal‐f® RFF* Redi‐ject® (follitropin alfa injection) is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program 

 For complete information, please see full Prescribing information here.

*RFF, Revised Formulation Female

Important Risk Information for Gonal-f® Multi-Dose (follitropin alfa for injection)

Do not use Gonal‐f® Multi-Dose if you:

  • Are allergic to recombinant human FSH or any of the ingredients listed on the product carton or insert
  • Have uncontrolled thyroid or adrenal problems
  • Have a tumor in your female organs, including your ovaries, breast, or uterus or permanent damage to the male sex organs (testes)
  • Have a tumor in your brain, such as a tumor in your pituitary 
  • Have abnormal bleeding from your uterus or vagina
  • Have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)
  • Are pregnant or think you may be pregnant

Before using Gonal‐f® Multi-Dose, tell your healthcare provider about your medical history including any prescription or over- the-counter medicines, vitamins and herbal supplements used, whether you have or have had asthma, abdominal surgery, ovarian cysts, polycystic ovarian disease, blood clots (thrombosis) or family history of blood clots, or are breastfeeding or plan to breastfeed.

Gonal‐f® Multi-Dose may cause serious side effects, including:

  • Ovarian hyperstimulation syndrome (OHSS) is a serious side effect. OHSS can be mild, moderate or severe, and in rare cases, has caused death. Mild symptoms can progress to more serious symptoms and immediate evaluation by your doctor is necessary. Early signs of OHSS include trouble breathing, severe lower stomach (pelvic) area pain, nausea, vomiting, weight gain. Call your health care provider right away. Symptoms include stomach pain, stomach bloating, nausea, vomiting and diarrhea, enlargement of ovaries, difficulty breathing and a drop in urine output
  • Gonal-f® Multi-Dose can also cause or worsen lung problems (including acute respiratory distress syndrome and asthma), blood and blood vessel problems (including clots and stroke) which in rare cases have caused death.
  • Use of Gonal‐f® Multi-Dose can result in pregnancy with more than one baby and the birth of multiple babies.
  • Stop using Gonal‐f® and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).

Other serious side effects include:

  • Gonal‐f® Multi-Dose can also cause or worsen lung problems (including asthma), blood and blood vessel problems (including clots and stroke), or twisting of your ovary, which require medical attention
  • Miscarriage, or ectopic pregnancy (pregnancy outside your womb)
  • Chances of having a baby with birth defects may increase in a baby born after an ART cycle and can be impacted by maternal age, paternal sperm problems, and genetic background associated with the egg and sperm.
  • It is not known if this drug is excreted in human milk. Because of the potential for serious adverse reactions in the nursing infant from Gonal-f, a decision should be made whether to stop nursing or stop the drug taking into account the importance of the drug to the mother.

The most common side effects of Gonal‐f® Multi-Dose include 

  • Headache 
  • Stomach pain 
  • Stomach bloating 
  • Bruising at the injection site,
  • Nausea
  • Other side effects reported include sinus infections and ovarian cysts.

In men, common side effects include 

  • Skin pimples 
  • Breast pain and growth
  • Tiredness.

These are not all the possible side effects of Gonal‐f®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® Multi-Dose as directed and do not change your dose unless directed. Do not share your Gonal‐f® Multi-Dose and needles with another person; you may give another person an infection or get an infection from them.

Carefully review the Gonal‐f® Multi‐Dose Patient Information Leaflet that comes with the product and follow all training and instruction provided by your healthcare provider. The injection syringes provided with the product should only be used with Gonal‐f® Multi‐Dose and should not be used to administer any other drug or hormone.

Indications and Usage

Gonal‐f® Multi-Dose is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • Help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • Cause your ovaries to make multiple (more than 1) eggs as part of an Assisted Reproductive Technology (ART) program

Gonal‐f® Multi-Dose can also be prescribed to increase sperm production in men with a rare medical condition.

 

Important Risk Information for Gonal-f® RFF* 75 IU (follitropin alfa for injection)

Do not use Gonal‐f® RFF* 75 IU if you:

  • are allergic to recombinant human FSH or any of the ingredients listed on the product carton or package insert
  • have levels of FSH indicating primary gonadal failure
  • have uncontrolled thyroid or adrenal problems
  • have a tumor in your female organs, including your ovaries, breast, or uterus
  • have a tumor in your brain, such as a tumor in your pituitary or hypothalamus
  • have abnormal uterine bleeding of undetermined origin
  • have ovarian cysts or large ovaries, not due to polycystic ovary syndrome (PCOS)
  • are pregnant or think you may be pregnant

Before using Gonal-f® RFF* 75 IU, tell your healthcare provider about your medical history including any prescription or over-the-counter medicines, vitamins and herbal supplements used.

Gonal‐f® RFF* 75 IU may cause serious side effects, including: 

  • Severe or fatal allergic reactions. Stop using Gonal‐f® RFF* 75 IU and go to the hospital right away if you have symptoms of an allergic reaction which can include shortness of breath, swelling of your face, itchy, red bumps or rash on your skin (hives).
  • Stomach bloating or pain caused by enlargement of your ovaries, or fluid build-up in your stomach, chest and heart caused by ovarian hyperstimulation syndrome (OHSS). OHSS can require hospitalization and in rare cases has caused death. Call your healthcare provider right away if you have symptoms of OHSS, including trouble breathing, severe lower stomach (pelvic) area pain, decreased urine output, nausea, vomiting, weight gain, and diarrhea. 
  • Gonal‐f® RFF* 75 IU can also cause or worsen lung problems (including asthma), blood and blood vessel problems (including clots and stroke), or twisting of your ovary, which require medical attention.
  • Use of Gonal‐f® RFF* 75 IU can result in pregnancy with more than one baby and the birth of multiple babies. 
  • It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in the nursing infant from Gonal-f® RFF* 75 IU, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

The most common side effects of Gonal‐f® RFF* 75 IU include headache, stomach pain, stomach bloating, bruising at the injection site, and nausea. Other side effects reported include sinus infections and ovarian cysts. 

These are not all the possible side effects of Gonal‐f® RFF* 75 IU. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Use Gonal‐f® RFF* 75 IU as directed and do not change your dose unless directed. Do not share your Gonal‐f® RFF* 75 IU and needles with another person; you may give another person an infection or get an infection from them.

Indications and Usage

Gonal‐f® RFF* 75 IU (follitropin alfa for injection) is a prescription medicine containing follicle‐stimulating hormone (FSH) used in infertile women to:

  • help ovulation and pregnancy in women who are infertile due to a cause other than primary ovarian failure
  • cause your ovaries to develop multiple (more than one) eggs as part of an Assisted Reproductive Technology (ART) program
*RFF, Revised Formulation Female

Important Risk Information for Cetrotide® (cetrorelix acetate for injection)

Who should not use Cetrotide®?

  • Patients that are allergic to cetrorelix acetate, mannitol, or exogenous peptide hormones (medicines similar to Cetrotide®) should not use Cetrotide®
  • If you have had severe allergic reactions to any drugs in a previous IVF cycle, tell your doctor.
  • Cetrotide® should not be used in patients who are pregnant, think they might be pregnant, or are breastfeeding.
  • Cetrotide® should not be used in patients with kidney disease.

Before starting Cetrotide®, tell your healthcare professional about all your medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

What is the most important information I should know before starting Cetrotide®?

  • Your doctor will confirm you are not pregnant.

What are the possible side effects of Cetrotide®?

Cetrotide® may cause serious side effects including:

  • Allergic reactions including anaphylactic reaction with the first dose. Treatment with Cetrotide® is not advised in women with severe allergic conditions.
  • Your doctor should review with you the risks and benefits of using Cetrotide®.
  • It is not known if Cetrotide® is excreted in human milk. Because the effects of Cetrotide® on nursing mothers or the nursing infant are not known, do not use Cetrotide® if you are breastfeeding.

Common side effects of using Cetrotide® include:

  • Mild and short-lasting reactions may occur at the injection site like reddening, itching, and swelling. Nausea and headache have also been reported.

Call your doctor if you have any other side effect or if you are unsure about the effect of this medicine.

These are not all the possible side effects of Cetrotide®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Indication

What are the uses of Cetrotide®?

Cetrotide® blocks the effects of a natural hormone, called gonadotropin-releasing hormone (GnRH). GnRH controls the secretion of another hormone, called luteinizing hormone (LH), which induces ovulation during the menstrual cycle.

Cetrotide® blocks undesirable premature ovulation. Premature ovulation may lead to eggs that are not available for egg retrieval.

 Please see full Prescribing information here.

Important Risk Information for Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)

Who should not use Ovidrel® PreFilled Syringe?

Ovidrel® Pre-Filled Syringe should not be used in patients:

  • With allergies to hCG or any other ingredients in the medication
  • With primary ovarian failure (the ovaries no longer produce eggs)
  • With uncontrolled thyroid or adrenal disease
  • Cancer of the brain such as pituitary tumor
  • With a history of abnormal bleeding from the uterus or vagina
  • With swollen, enlarged, or painful ovaries
  • With cancer of the sex organs
  • Who are pregnant 

Before starting Ovidrel®, tell your healthcare professional about all your medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What is the most important information I should know before taking Ovidrel?

  • Mild to moderate uncomplicated ovarian enlargement which may be accompanied by abdominal distention and/or abdominal pain may occur in patients treated with FSH and hCG. 
  • Ovarian Hyperstimulation Syndrome (OHSS) may progress rapidly from uncomplicated ovarian enlargement and become a serious medical event. Early signs of OHSS include severe pelvic pain, nausea, vomiting, and weight gain. Call your doctor right away if you think you might be having symptoms of OHSS.
  • Treatment with Ovidrel® may result in becoming pregnant with more than one baby.
  • Blood clots may result from treatment with Ovidrel®.
  • It is not known whether this drug is present in human milk. Because many drugs are excreted in human milk, tell your doctor if you are nursing.

What are the most common side effects of Ovidrel® Pre-Filled Syringe?

The most common side effects in women using Ovidrel® Pre-Filled Syringe include abdominal pain, nausea, and vomiting. Needle injections may cause some discomfort.

These are not all the possible side effects of Ovidrel®. For more information, read the product labeling, and ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1‐800‐FDA‐1088.

Indication

What are the uses of Ovidrel® Pre-Filled Syringe (choriogonadotropin alfa for injection)?

Ovidrel® Pre-Filled Syringe (choriogonadotropin alfa injection) is indicated for the final egg maturation to get ready for egg retrieval. Women who receive Ovidrel® have undergone pituitary desensitization and have been appropriately pre-treated with follicle stimulating hormone (FSH) as a part of an Assisted Reproductive Technology (ART) program such as in vitro (IVF) fertilization and embryo transfer.

Ovidrel® Pre-Filled Syringe is also indicated for the induction of ovulation (OI) and pregnancy in infertile patients who do not ovulate, and in whom the cause of infertility is functional and not due to primary ovarian failure

 For complete information, please see full Prescribing information here.

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